Early Disease Diagnostics
Focusing on the early detection and treatment of diseases like Cancer.
Early detection of diseases like Cancer, Alzheimer's, and Parkinson's
The human microbiome comprises a collection of dynamic microbial communities that inhabit various anatomical locations in the body. The microbiome's coevolution with the host results in a strong connection to human health.
I am part of the SAFARI Research Group of ETH and CMU, mentored by Prof. Onur Mutlu. I develop bioinformatics algorithms and AI/ML techniques to analyze the microbiome from liquid biopsy samples, aiming to identify early indications of diseases such as cancer, Alzheimer's, and Parkinson's.
Key Publications
Gollwitzer, Arvid, Mohammed Alser, Joel Bergtholdt, Joel Lindegger, Maximilian-David Rumpf, Can Firtina, Serghei Mangul and Onur Cezmi Mutlu. “MetaTrinity: Enabling Fast Metagenomic Classification via Seed Counting and Edit Distance Approximation.” (2023).
Rumpf, Maximilian-David, Mohammed Alser, Arvid Gollwitzer, Joel Lindegger, Nour Almadhoun, Can Firtina, Serghei Mangul and Onur Cezmi Mutlu. “SequenceLab: A Comprehensive Benchmark of Computational Methods for Comparing Genomic Sequences.” ArXiv abs/2310.16908 (2023).
Mansouri-Ghiasi, Nika, Jisung Park, Harun Mustafa, Jeremie S. Kim, Ataberk Olgun, Arvid Gollwitzer, Damla Senol Cali, Can Firtina, Haiyu Mao, Nour Almadhoun Alserr, Rachata Ausavarungnirun, Nandita Vijaykumar, Mohammed Alser and Onur Mutlu. “GenStore: a high-performance in-storage processing system for genome sequence analysis.” Proceedings of the 27th ACM International Conference on Architectural Support for Programming Languages and Operating Systems (2022).